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beta-Lipotropin - Cat #:MV1004
Product Description Rabbit polyclonal antibody to N-terminal portion of human beta Lipotropin conjugated to thyroglobulin
beta-Lipotropin Immunohistochemical staining of beta-Lipotropin in mouse brain. 4% paraformaldehyde fixed rat brain 10 μm thick cryostat sections were incubated with rabbit polyclonal antibody to beta-Lipotropin at 10 μg/mL overnight at 4°C followed by incubation with Donkey anti-rabbit Rhodamine Red conjugated secondary antibodies at 1:200. Tissue was counterstained with DAPI (blue color) to visualize cell nuclei.
Formulation Lyophilized from 10 mM PBS.
Purification Whole IgG
Host Species Rabbit
Unit Size: 50 µg
Immunogen human beta Lipotropin conjugated to thyroglobulin.
Antigen Location (aa): 179 - 267
Alternative Names beta-LPH
Accession Number: P01189
Accession Name: COLI_HUMAN
Accession URL:
Function: beta-Lipotropin is a 90-amino acid polypeptide that is the carboxy-terminal fragment of POMC. It stimulates melanocytes to produce melanin, and can also be cleaved into smaller peptides including opioid peptides: gamma-lipotropin, alpha-MSH, beta-MSH, gamma-MSH, alpha-endorphin, beta-endorphin, gamma-endorphin and met-enkephalin.
Applications: Recommended for Immunohistochemistry (IHC) and Cytochemistry (ICC).
Working Dilution for Immunofluorescence (ICC): 5 – 15 µg/ml
Working Dilution for Immunohistochemistry (IHC): 5 – 10 µg/ml
IHC Positive control: Brain
Specificity: Confirmed by RIA against the synthetic peptide.
Cross-reactivity: Human; mouse; rat. Beta-endorphin is a highly conserved molecule, so cross-reactivity with other species is expected. Cross-reactivity with other opioid peptides is as follows: with Met-enkephalin 0.03%; with Leu-enkephalin 0.02%; with beta-lipotropin 0.34%.
Reconstitution: Reconstitute in 0.05 ml of PBS (pH 7.4) to achieve an antibody concentration of 1000 µg/ml. Centrifuge to remove any insoluble material.
Storage / Stability: At least 12 months after purchase at 2 - 4°C. After reconstitution, aliquot and store at -20°C for a higher stability and at 4°C with an appropriate antibacterial agent. Avoid freeze-thaw cycles.
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  6. Kuhla B, Albrecht D, Bruckmaier R, Viergutz T, Nürnberg G, Metges CC. Proteomics. 2010 Oct 14. 21105009.

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