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Somatostatin (Cat #: MV1012)
Product Description Rabbit polyclonal antibody to the human Somatostatin conjugated to BSA.
Somatostatin Immunohistochemical staining of Somatostatin in rat brainstem medulla. 4% paraformaldehyde fixed rat brain 10 μm thick cryostat sections were incubated with rabbit polyclonal antibody to Somatostatin at 10 μg/mL overnight at 4°C followed by incubation with Donkey anti-rabbit Rhodamine Red (pseudo-coloured yellow) conjugated secondary antibodies at 1:200. Cell nuclei were counterstained with DAPI.
Formulation Lyophilized from 10 mM PBS.
Purification Whole IgG
Host Species Rabbit
Unit Size: 50 µg
Immunogen Somatostatin conjugated to BSA.
Antigen Location (aa): 103-116
Alternative Names Growth hormone release-inhibiting factor (SRIF), growth hormone-inhibiting hormone (GHIH).
Accession Number: P61278
Accession Name: (SMS_HUMAN)
Accession URL:
Function: Somatostatin is secreted by neuroendocrine neurons in hypothalamus and interacts with somatostatin receptors inhibiting secretion of growth hormone.
Applications: Recommended for Immunohistochemistry (IHC) and Cytochemistry (ICC).
Working Dilution for Immunofluorescence (ICC): 5 – 15 µg/mL
Working Dilution for Immunohistochemistry (IHC): 5 – 10 µg/mL
IHC Positive control: Brainstem medulla
Specificity: Confirmed by RIA against the synthetic peptide.
Cross-reactivity: Human, mouse, rat.
Reconstitution: Reconstitute in 0.05 mL of PBS (pH 7.4) to achieve an antibody concentration of 1000 µg/mL. Centrifuge to remove any insoluble material
Storage / Stability: At least 12 months after purchase at 2 - 4°C. After reconstitution, aliquot and store at -20°C for a higher stability and at 4°C with an appropriate antibacterial agent. Avoid freeze-thaw cycles.
  1. Hokfelt T, Efendic S, Johansson O, Luft R, Arimura A. Immunohistochemical localization of somatostatin (growth hormone release-inhibiting factor) in the guinea pig brain. Brain Res 1974 Nov 8;80(1):165-9. PMID: 4608681.
  2. Elde R, Hokfelt T, Johansson O, Schultzberg M, Efendic S, Luft R. Cellular localization of somatostatin Metabolism 1978 Sep;27(9 Suppl 1):1151-9. PMID: 355778.
  3. Bowker RM. Evidence for the co-localization of somatostatin- and methionine-enkephalin-like immunoreactivities in raphe and gigantocellularis nuclei. Neurosci Lett 1987 Oct 16;81(1-2):75-81. PMID: 2892158.
  4. Maley BE. Immunohistochemical localization of neuropeptides and neurotransmitters in the nucleus solitarius. Chem Senses 1996 Jun;21(3):367-76. PMID: 8670716.
  5. Lepousez G, Csaba Z, Bernard V, Loudes C, Videau C, Lacombe J, Epelbaum J, Viollet C. J Comp Neurol. 2010 Jun 1;518(11):1976-94.PMID: 20394054.

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